Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822201 | 0.89 | NAMPT (0.65) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6738542 | 0.87 | TP53 (0.54) | ALDH1A1LMNAMAPTHTTPOLB | |
| SCHEMBL6743382 | 0.86 | NAMPT (0.61) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6743558 | 0.82 | NAMPT (0.51) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7258750 | 0.81 | KEAP1 (0.51) | HTTGAA | |
| SCHEMBL6741490 | 0.80 | KMT2A (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8211195 | 0.78 | NAMPT (0.68) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6350923 | 0.77 | GAA (0.79) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL2056379 | 0.77 | NAMPT (0.67) | NAMPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11563747 | 0.76 | NAMPT (0.77) | NAMPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | NQO2, SULT1A1, NAT1 | NAMPT 1191/4885KMT2A 531/4885MEN1 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.