Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743562 | 0.83 | TP53 (0.50) | TP53LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6740788 | 0.80 | ALDH1A1 (0.61) | TP53LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6352552 | 0.79 | RAB9A (0.64) | TP53LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6743558 | 0.78 | NAMPT (0.51) | LMNAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL7929176 | 0.75 | RAB9A (0.50) | TP53LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1342005 | 0.73 | SMN1; SMN2 (0.61) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6349839 | 0.72 | MAPT (0.47) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6353244 | 0.72 | CA1 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13827423 | 0.72 | CYP17A1 (0.48) | TP53LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL21059104 | 0.71 | SMN1; SMN2 (0.65) | TP53LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | NQO2, SULT1A1, NAT1 | TP53 1326/4885LMNA 1575/4885NPC1 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.