P-Cymene

P-Cymene

SCHEMBL6740530

COc1ccc(S(=O)(=O)N[C@@H](c2ccccc2)[C@@H](N)c2ccccc2)cc1.Cc1ccc(C(C)C)cc1.[Ru]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.51
ALDH1A1 P00352 6/20 0.46
POLB P06746 1/20 0.46
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TP53 P04637 1/20 0.41
MMP9 P14780 2/20 0.41
MMP2 P08253 2/20 0.41
MMP1 P03956 1/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cymene SCHEMBL7513368 1.00 CNR1 (0.51) CNR1ALDH1A1POLBSLC1A3SLC1A2
P-Cymene SCHEMBL2240125 0.92 ALDH1A1 (0.50) ALDH1A1SLC1A3SLC1A2SLC1A1NPSR1
P-Cymene SCHEMBL3579869 0.92 ALDH1A1 (0.50) ALDH1A1SLC1A3SLC1A2SLC1A1NPSR1
P-Cymene SCHEMBL7527837 0.90 NPSR1 (0.47) ALDH1A1SLC1A3SLC1A2SLC1A1NPSR1
P-Cymene SCHEMBL6743208 0.90 NPSR1 (0.47) ALDH1A1SLC1A3SLC1A2SLC1A1NPSR1
SCHEMBL12674763 0.90 CNR1 (0.57) CNR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL13566636 0.90 CNR1 (0.57) CNR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL12446983 0.90 CNR1 (0.57) CNR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL10054196 0.90 CNR1 (0.57) CNR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL26666235 0.90 CNR1 (0.57) CNR1ALDH1A1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696573-B1 SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-02-24 US disclosed
EP-1195371-A1 PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES Asahi Kasei Kabushiki Kaisha (JP) 2002-04-10 EP disclosed
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed