Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cymene SCHEMBL2240125 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Cymene SCHEMBL7527837 | 0.97 | NPSR1 (0.47) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Cymene SCHEMBL6743208 | 0.97 | NPSR1 (0.47) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Cymene SCHEMBL3341178 | 0.96 | NPSR1 (0.49) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Cymene SCHEMBL7517875 | 0.94 | ALDH1A1 (0.46) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Cymene SCHEMBL6740633 | 0.94 | ALDH1A1 (0.46) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| Benzene SCHEMBL3854289 | 0.93 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28382647 | 0.93 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3342411 | 0.93 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Xylene SCHEMBL5421492 | 0.93 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7332622-B2 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2008-02-19 | — | — | US | disclosed |
| US-7268250-B2 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2007-09-11 | — | — | US | disclosed |
| EP-1308435-B1 | Process for producing optically active amino alcohols | KANTO KAGAKU (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1512678-A1 | Process for preparing optically active nitro compounds and cyano compounds | Kanto Kagaku Kabushiki Kaisha (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-20040176616-A1 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA | 2004-09-09 | — | — | US | disclosed |
| US-6686505-B2 | HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1308435-A2 | Process for producing optically active amino alcohols | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6495701-B1 | THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1174426-A1 | METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | ADH1A, NOS1, ADH5 | ALDH1A1 151/4885NPSR1 1710/4885SLC1A3 233/4885 |
| US-20040176616-A1 | Process for producing optically active compound | OSTC, NPEPPS, PPOX | ALDH1A1 3566/4885NPSR1 3017/4885SLC1A3 4283/4885 |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | NOS1, NOS2, NOX1 | ALDH1A1 1008/4885NPSR1 2609/4885SLC1A3 1768/4885 |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | OPRD1, OPRM1, OPRK1 | ALDH1A1 66/4885NPSR1 13/4885SLC1A3 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.