P-Cymene

P-Cymene

SCHEMBL6743208

Cc1ccc(C(C)C)cc1.N[C@@H](c1ccccc1)[C@@H](NS(=O)(=O)c1ccccc1)c1ccccc1.[Ru]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.47
ALDH1A1 P00352 3/20 0.47
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
HTT P42858 2/20 0.42
CNR2 P34972 1/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
HPN P05981 2/20 0.40
TP53 P04637 1/20 0.40
PLAU P00749 1/20 0.40
GBA1 P04062 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
CA7 P43166 2/20 0.39
BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cymene SCHEMBL7527837 1.00 NPSR1 (0.47) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL2240125 0.97 ALDH1A1 (0.50) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL3579869 0.97 ALDH1A1 (0.50) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL3341178 0.94 NPSR1 (0.49) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL6740633 0.92 ALDH1A1 (0.46) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL7517875 0.92 ALDH1A1 (0.46) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL4857445 0.91 NPSR1 (0.45) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
P-Cymene SCHEMBL4855141 0.91 NPSR1 (0.45) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL28382647 0.91 ALDH1A1 (0.52) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL3342411 0.91 ALDH1A1 (0.52) NPSR1ALDH1A1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696573-B1 SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-02-24 US disclosed
EP-1195371-A1 PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES Asahi Kasei Kabushiki Kaisha (JP) 2002-04-10 EP disclosed
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed