SCHEMBL6740983

SCHEMBL6740983

CC(C)COC(=O)CCCS

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
TSHR P16473 5/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.42
ATM Q13315 1/20 0.42
EPHX2 P34913 1/20 0.41
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PRKCA P17252 2/20 0.39
PRKCE Q02156 1/20 0.39
PRKCQ Q04759 1/20 0.39
PRKCD Q05655 1/20 0.39
DGKA P23743 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738675 0.87 TSHR (0.43) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL356035 0.87 MAPT (0.53) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL42941 0.87 MAPT (0.59) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL3086359 0.86 LMNA (0.46) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL496450 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL494408 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL495250 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL495181 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL495197 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1
SCHEMBL18786502 0.85 MAPT (0.62) MAPTTSHRLMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides DDT, HAX1, SULT1E1 MAPT 2566/4885TSHR 762/4885LMNA 4564/4885
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 MAPT 3418/4885TSHR 1003/4885LMNA 4573/4885
US-20030216257-A1 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides CYP1B1, DDT, CYP1A1 MAPT 4036/4885TSHR 706/4885LMNA 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.