Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740983 | 0.87 | MAPT (0.47) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL29930756 | 0.86 | MAPT (0.41) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL334176 | 0.85 | TSHR (0.50) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL4988228 | 0.85 | MAPT (0.38) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL98334 | 0.85 | LMNA (0.41) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL2127406 | 0.84 | MAPT (0.58) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL27561555 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL30529014 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL6355099 | 0.83 | MAPT (0.39) | TSHRMAPTALDH1A1TDP1LMNA | |
| SCHEMBL4983415 | 0.82 | MAPT (0.40) | TSHRMAPTGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410151-B | 3- (5, 5-Dimethyl-4, 5-dihydro-isoxazol-3-yl) propionate and synthetic method and application thereof | 山东润博生物科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-118666690-A | Binuclear quaternary ammonium salt ionic liquid compound and application thereof | 中国药科大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-116410151-A | 3- (5, 5-dimethyl-4, 5-dihydroxyisoxazol-3-yl) propionate and synthetic method and application thereof | 山东润博生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-113121763-A | Acrylate comb dispersant, organic pigment color paste and preparation method thereof | 传美讯电子科技（珠海）有限公司 | 2021-07-16 | — | — | CN | disclosed |
| US-10034861-B2 | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors | H. LUNDBECK A/S (DK) | 2018-07-31 | — | — | US | disclosed |
| US-20180000786-A1 | 1H-Pyrazolo[4,3-b]pyridines as PDE1 Inhibitors | H. LUNDBECK A/S (DK) | 2018-01-04 | — | — | US | disclosed |
| EP-2799455-A2 | Resin composition for optical member and optical member obtained from the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-7623751-B2 | Compound, polymerizable composition, optical device, and method for producing refractive index profile optical device | FUJIFILM CORPORATION (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7623751-B2 | Compound, polymerizable composition, optical device, and method for producing refractive index profile optical device | FUJIFILM CORPORATION (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20080226244-A1 | Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device | FUJIFILM CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-0080969-B1 | A METHOD OF REMOVING RESIDUAL ACRYLONITRILE FROM LATEX SYSTEMS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |
| EP-0097791-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-MERCAPTOPROPIONIC ACID | Degussa Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0097791-A1 | Process for the preparation of derivatives of 3-mercaptopropionic acid | Degussa Aktiengesellschaft (DE) | 1984-01-11 | — | — | EP | disclosed |
| US-4399253-A | REACTION WITH THIOL | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0080969-A1 | A method of removing residual acrylonitrile from latex systems | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4361665-A | ANTIMONY STABILIZER, ORTHO-DIHYDRIC PHENOL CHAIN STOPPER | TENNECO CHEMICALS, INC. (US) | 1982-11-30 | — | — | US | disclosed |
| US-4336168-A | ORGANIC SULFUR COMPOUNDS | TENNECO CHEMICALS, INC. (US) | 1982-06-22 | — | — | US | disclosed |
| EP-0039159-A1 | Vinyl halide resin compositions containing antimony-based stabilizer compositions, such stabilizer compositions and processes of production thereof | Nuodex Inc. (US) | 1981-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | TSHR 762/4885MAPT 2566/4885POLB 3943/4885 |
| US-10034861-B2 | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors | PDE3A, PDE5A, PDE12 | TSHR 2941/4885MAPT 246/4885POLB 1097/4885 |
| US-20180000786-A1 | 1H-Pyrazolo[4,3-b]pyridines as PDE1 Inhibitors | PDE3A, PDE5A, PDE12 | TSHR 2941/4885MAPT 246/4885POLB 1097/4885 |
| US-20080226244-A1 | Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device | PIEZO1, PFN1, INF2 | TSHR 2398/4885MAPT 2002/4885POLB 1299/4885 |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | CYP1B1, DDT, CYP1A1 | TSHR 706/4885MAPT 4036/4885POLB 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.