Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745519 | 0.92 | APP (0.36) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6745669 | 0.91 | TSHR (0.43) | TSHRGAAPDE5A | |
| SCHEMBL6740895 | 0.90 | TSHR (0.34) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6739659 | 0.89 | TSHR (0.43) | TSHRGAAPDE5A | |
| SCHEMBL6742027 | 0.89 | TSHR (0.35) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6741015 | 0.89 | DGAT2 (0.33) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6846143 | 0.89 | ALDH1A1 (0.33) | TSHRALDH1A1GAA | |
| SCHEMBL6739900 | 0.88 | TSHR (0.33) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6741898 | 0.88 | TSHR (0.34) | TSHRALDH1A1GAAPDE5A | |
| SCHEMBL6741815 | 0.88 | FYN (0.36) | TSHRALDH1A1GAAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152714-A1 | Benzylaminopyrimidines | ALTANA PHARMA AG (DE) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152714-A1 | Benzylaminopyrimidines | DPYD, PGLS, TPMT | TSHR 2503/4885PTGER1 698/4885ALDH1A1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.