Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.61 |
| ▸ | MEN1 | O00255 | 12/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16930808 | 0.87 | MEN1 (0.49) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL446946 | 0.83 | L3MBTL1 (0.52) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL30681806 | 0.83 | LTA4H (0.49) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL28135254 | 0.83 | NPC1 (0.77) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL18732403 | 0.83 | KMT2A (0.61) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL21003801 | 0.83 | KMT2A (0.61) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL7014701 | 0.83 | CLK4 (0.61) | NPC1RAB9ALTA4HALDH1A1 | |
| SCHEMBL18731741 | 0.83 | KMT2A (0.61) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL29730468 | 0.83 | KMT2A (0.61) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL190954 | 0.82 | AURKA (0.63) | KMT2AMEN1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | MAP3K20, MAP3K1, MAP3K19 | KMT2A 489/4885MEN1 1773/4885MAPT 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.