Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL675298 | 0.88 | NPC1 (0.36) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL1235559 | 0.87 | NPC1 (0.34) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL7107213 | 0.85 | NPC1 (0.32) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL7945483 | 0.84 | PNMT (0.32) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL7101775 | 0.84 | PNMT (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL674628 | 0.83 | NPC1 (0.32) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL7945478 | 0.83 | NPC1 (0.32) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL674865 | 0.83 | PNMT (0.32) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL7934594 | 0.82 | PNMT (0.31) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL674169 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237461-B1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2026-03-18 | — | — | EP | disclosed |
| US-10787545-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-09-29 | — | — | US | disclosed |
| US-20200262983-A1 | PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-20 | — | — | US | disclosed |
| US-10717826-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-07-21 | — | — | US | disclosed |
| EP-3233974-B1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-02-19 | — | — | EP | disclosed |
| US-10472447-B2 | Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-12 | — | — | US | disclosed |
| US-10465018-B2 | Process for the preparation of a polyolefin having one or multiple end-functionalized branches | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-10450388-B2 | Process for the preparation of a branched polyolefin | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-22 | — | — | US | disclosed |
| EP-3034546-B1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| EP-3034544-B1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| US-20080306219-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST | IKENAGA SHIGENOBU | 2008-12-11 | — | — | US | disclosed |
| US-20080292896-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST | IKENAGA SHIGENOBU | 2008-11-27 | — | — | US | disclosed |
| EP-1988104-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1985637-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| EP-1985638-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20060276607-A1 | Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization | MITSUI CHEMICALS, INC. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |
| EP-0786466-B1 | Olefin polymerisation process which comprises a transition metal catalyst. | TOSOH CORP (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0786466-A1 | Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer | Tosoh Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |