Hydrochloric Acid

Hydrochloric Acid

SCHEMBL675298

CC(C)=[Zr+2](C1=CC(C(C)(C)C)=CC1)c1cccc2c1Cc1ccccc1-2.[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PNMT P11086 1/20 0.32
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL674164 0.88 NPC1 (0.32) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL1235499 0.86 NPC1 (0.39) NPC1RAB9APNMTHTR7HTR2B
Hydrochloric Acid SCHEMBL3123247 0.82 PNMT (0.32) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL9067118 0.82 PNMT (0.32) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL676211 0.82 NPC1 (0.36) NPC1RAB9APNMTHTR7HTR2B
Hydrochloric Acid SCHEMBL675641 0.82 NPC1 (0.36) NPC1RAB9APNMTHTR7HTR2B
Hydrochloric Acid SCHEMBL3124487 0.80 NPC1 (0.49) NPC1RAB9APNMTHTR7HTR2B
Hydrochloric Acid SCHEMBL28642357 0.79 PNMT (0.30) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL675461 0.79 PNMT (0.30) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL673491 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237461-B1 PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-03-18 EP disclosed
US-11859316-B2 Process for the production of fibers TOTALENERGIES ONETECH BELGIUM (BE) 2024-01-02 US disclosed
US-11180583-B2 Polyalphaolefin having uniform structure and method of preparing same DL CHEMICAL CO., LTD. (KR) 2021-11-23 US disclosed
US-10787545-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-29 US disclosed
US-20200262983-A1 PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
US-10717826-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-21 US disclosed
EP-3660133-A1 POLYALPHAOLEFIN HAVING UNIFORM STRUCTURE AND METHOD OF PREPARING SAME Daelim Industrial Co., Ltd. (KR) 2020-06-03 EP disclosed
US-20200165362-A1 POLYALPHAOLEFIN HAVING UNIFORM STRUCTURE AND METHOD OF PREPARING SAME DAELIM INDUSTRIAL CO., LTD. (KR) 2020-05-28 US disclosed
EP-3233974-B1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
US-10472447-B2 Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-12 US disclosed
EP-1092730-A1 PROCESS FOR PRODUCING OLEFIN POLYMER AND OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2001-04-18 EP disclosed
US-6136743-A WIDE MOLECULAR WEIGHT DISTRIBUTION; METALLOCENE COMPOUND OR A TITANIUM CATALYST COMPONENT CONTAINING MAGNESIUM, TITANIUM, AND HALOGEN; A NITROGEN OR PHOSPHORUS COMPLEX OF A TRANSITION METAL FROM GROUPS 8 TO 10 OF THE PERIODIC TABLE; COCATALYST MITSUI CHEMICALS, INC. (JP) 2000-10-24 US disclosed
US-6063871-A SPECIFIC HIGH-DENSITY ETHYLENE POLYMER AND A SPECIFIC ETHYLENE POLYMER, IN WHICH AT LEAST ONE IS PREPARED USING A METALLOCENE CATALYST, AND THE DENSITY RATIO THEREBETWEEN EXCEEDS 1; MOLDABILITY, CRACK RESISTANCE, STRENGTH AND RIGIDITY MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 2000-05-16 US disclosed
US-5942459-A ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER MITSUBISHI CHEMICAL CORPORATION (JP) 1999-08-24 US disclosed
EP-0924223-A2 Catalyst component, catalyst and process for ethylenically unsaturated monomer polymerization Mitsui Chemicals, Inc. (JP) 1999-06-23 EP disclosed
US-5883275-A Process for the hydrogenation of metallocenes TARGOR GMBH (DE) 1999-03-16 US disclosed
EP-0728773-B1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEM CORP (JP) 1998-11-04 EP disclosed
EP-0786466-A1 Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer Tosoh Corporation (JP) 1997-07-30 EP disclosed
EP-0783022-A1 ETHYLENIC POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-09 EP disclosed
EP-0728773-A1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-28 EP disclosed