Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5402653 | 0.74 | TDP1 (0.46) | TAAR1SLC6A3SLC6A4CACNA1FCHRM2 | |
| SCHEMBL24453542 | 0.72 | CACNA1F (0.43) | TAAR1SLC6A3CACNA1FCHRM2CHRM1 | |
| SCHEMBL6226291 | 0.69 | CHRM2 (0.44) | SLC6A3SLC6A2SLC6A4CACNA1FCHRM2 | |
| SCHEMBL6248389 | 0.69 | SIGMAR1 (0.55) | TAAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6741704 | 0.68 | BACE1 (0.39) | TAAR1SLC6A3SLC6A2SLC6A4KIF11 | |
| SCHEMBL19361268 | 0.68 | MAPT (0.48) | CHRM2CHRM1CHRM3KCNH2KIF11 | |
| SCHEMBL3640366 | 0.67 | TAAR1 (0.50) | TAAR1SLC6A3SLC6A2SLC6A4CACNA1F | |
| SCHEMBL5969931 | 0.67 | HDAC3 (0.44) | KIF11CYP1A2KCNN4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9796807 | 0.67 | KCNN4 (0.36) | TAAR1SLC6A3CACNA1FCHRM2CHRM1 | |
| SCHEMBL20357562 | 0.66 | KIF11 (0.64) | TAAR1KIF11KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229838-A1 | Purine derivatives | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229838-A1 | Purine derivatives | ADORA2A, ADORA1, ADORA3 | TAAR1 92/4885SLC6A3 515/4885SLC6A2 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.