SCHEMBL6741972

SCHEMBL6741972

CCCCCCOc1cc2c3cc(OCCCCCC)c(OCCCCCC)cc3c3cc(OC(=O)c4ccc([N+](=O)[O-])cc4)c(OCCCCCC)cc3c2cc1OCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.48
CYSLTR2 Q9NS75 1/20 0.47
CYSLTR1 Q9Y271 1/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MGLL Q99685 1/20 0.46
ESR1 P03372 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PKM P14618 1/20 0.44
PLA2G4B P0C869 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6737400 0.89 ALOX5 (0.48) CYP19A1CYSLTR2CYSLTR1THRATHRB
SCHEMBL6737597 0.83 SMPD1 (0.47) THRATHRBALDH1A1MAPT
SCHEMBL12732262 0.82 PTPN11 (0.50) ALDH1A1POLBMAPT
SCHEMBL3616954 0.81 NPC1 (0.64) MGLLL3MBTL1PKMPLA2G4BPOLB
SCHEMBL13325797 0.81 NPC1 (0.64) MGLLL3MBTL1PKMPLA2G4BPOLB
SCHEMBL8377915 0.81 NPC1 (0.64) MGLLL3MBTL1PKMPLA2G4BPOLB
SCHEMBL30132301 0.81 NPC1 (0.64) MGLLL3MBTL1PKMPLA2G4BPOLB
SCHEMBL14262015 0.81 NPC1 (0.63) PLA2G4BPOLBMAPT
SCHEMBL7587876 0.81 NPC1 (0.63) PLA2G4BPOLBMAPT
SCHEMBL9325684 0.81 NPC1 (0.63) PLA2G4BPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689290-B2 Family of conducting liquid crystals THE UNIVERSITY OF LEEDS (GB) 2004-02-10 US claimed
US-20030160212-A1 New family of conducting liquid crystals UNIVERSITY OF LEEDS, THE (GB) 2003-08-28 US claimed
US-6689290-B2 Family of conducting liquid crystals THE UNIVERSITY OF LEEDS (GB) 2004-02-10 US disclosed
US-20030160212-A1 New family of conducting liquid crystals UNIVERSITY OF LEEDS, THE (GB) 2003-08-28 US disclosed
EP-1240272-A2 A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS THE UNIVERSITY OF LEEDS (GB) 2002-09-18 EP disclosed
WO-2001042391-A2 A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS UNIVERSITY OF LEEDS (GB) 2001-06-14 WO disclosed