Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732262 | 0.86 | PTPN11 (0.50) | SMPD1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL4780156 | 0.86 | THRA (0.60) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL7587876 | 0.85 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL4531460 | 0.85 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262015 | 0.85 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262013 | 0.85 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9325684 | 0.85 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL6739007 | 0.85 | PTPN11 (0.54) | SMPD1THRATHRBALDH1A1HPGD | |
| SCHEMBL6737583 | 0.84 | ALDH1A1 (0.54) | SMPD1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL6741972 | 0.83 | CYP19A1 (0.48) | THRATHRBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689290-B2 | Family of conducting liquid crystals | THE UNIVERSITY OF LEEDS (GB) | 2004-02-10 | — | — | US | claimed |
| US-20030160212-A1 | New family of conducting liquid crystals | UNIVERSITY OF LEEDS, THE (GB) | 2003-08-28 | — | — | US | claimed |
| US-6689290-B2 | Family of conducting liquid crystals | THE UNIVERSITY OF LEEDS (GB) | 2004-02-10 | — | — | US | disclosed |
| US-20030160212-A1 | New family of conducting liquid crystals | UNIVERSITY OF LEEDS, THE (GB) | 2003-08-28 | — | — | US | disclosed |
| EP-1240272-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | THE UNIVERSITY OF LEEDS (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042391-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | UNIVERSITY OF LEEDS (GB) | 2001-06-14 | — | — | WO | disclosed |