SCHEMBL6742186

SCHEMBL6742186

CN1CN(C)c2c1[nH]c(=O)[nH]c2=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 11/20 0.37
▸ GDA Q9Y2T3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28735867 0.73 EPHX2 (0.34) —
SCHEMBL7559507 0.67 TYMP (0.37) TYMPGDA
SCHEMBL9844559 0.66 TYMP (0.31) TYMP
SCHEMBL29148112 0.65 EPHX2 (0.42) —
SCHEMBL11036684 0.65 TYMP (0.32) TYMPGDA
SCHEMBL1586365 0.62 PNP (0.37) —
SCHEMBL228923 0.57 — —
SCHEMBL12252009 0.57 — —
SCHEMBL34461920 0.54 IDH1 (0.41) TYMPGDA
SCHEMBL1977724 0.54 IDH1 (0.41) TYMPGDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040013609-A1 For identification of substances for treatment or prevention of insufficient longitudinal growth of eye(hypermetropia) or excessive longitudinal growth of eye(myopia); involves measurement of effect on retinal pigment epithelium TRIER KLAUS (DK) 2004-01-22 — — US claimed
WO-1998030900-A2 SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA KLAUS TRIER APS (DK) 1998-07-16 — — WO claimed
EP-3356440-B1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS PURDUE RESEARCH FOUNDATION (US) 2024-06-05 — — EP disclosed
WO-2023185709-A1 MARKER COMBINATION FOR DIAGNOSING ADVANCED COLORECTAL TUMOR, AND APPLICATION THEREOF 武汉迈特维尔医学科技有限公司 2023-10-05 — — WO disclosed
US-20220257770-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS PURDUE RESEARCH FOUNDATION (US) 2022-08-18 — — US disclosed
US-11052153-B2 Highly branched alpha-D-glucans PURDUE RESEARCH FOUNDATION (US) 2021-07-06 — — US disclosed
US-20200268894-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS PURDUE RESEARCH FOUNDATION (US) 2020-08-27 — — US disclosed
US-10653784-B2 Hydrophobic highly branched carbohydrate polymers PURDUE RESEARCH FOUNDATION (US) 2020-05-19 — — US disclosed
US-20190038753-A1 HIGHLY BRANCHED ALPHA-D-GLUCANS PURDUE RESEARCH FOUNDATION (US) 2019-02-07 — — US disclosed
US-10117937-B2 Highly branched alpha-D-glucans PURDUE RESEARCH FOUNDATION (US) 2018-11-06 — — US disclosed
US-20180289815-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS PURDUE RESEARCH FOUNDATION (US) 2018-10-11 — — US disclosed
EP-3356440-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS PHYTOPTION, LLC (US) 2018-08-08 — — EP disclosed
CN-104379175-B Highly branched α -D-glucan 普渡研究基金会 2018-08-07 — — CN disclosed
US-20150080220-A1 HIGHLY BRANCHED ALPHA-D-GLUCANS PHYTOPTION, LLC. 2015-03-19 — — US disclosed
EP-2838564-A1 HIGHLY BRANCHED ALPHA-D-GLUCANS Purdue Research Foundation (US) 2015-02-25 — — EP disclosed
CN-104379175-A Highly branched alpha-D-glucans PURDUE RESEARCH FOUNDATION 2015-02-25 — — CN disclosed
WO-2013158992-A1 HIGHLY BRANCHED ALPHA-D-GLUCANS PURDUE RESEARCH FOUNDATION (US) 2013-10-24 — — WO disclosed
US-6710051-B1 SUBSTANCES IS A XANTHINE AND IS ADMINISTERED IN A DOSAGE OF 7.5-750 MG 1-4 TIMES DAILY TO TREAT MYOPIA KLAUS TRIER APS (DK) 2004-03-23 — — US disclosed
US-20040013609-A1 For identification of substances for treatment or prevention of insufficient longitudinal growth of eye(hypermetropia) or excessive longitudinal growth of eye(myopia); involves measurement of effect on retinal pigment epithelium TRIER KLAUS (DK) 2004-01-22 — — US disclosed
WO-1998030900-A2 SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA KLAUS TRIER APS (DK) 1998-07-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10653784-B2 Hydrophobic highly branched carbohydrate polymers HACD3, ALG1, HACD2 TYMP 1741/4885GDA 2595/4885
US-20200268894-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS HACD3, ALG1, HACD2 TYMP 1741/4885GDA 2595/4885
US-20040013609-A1 For identification of substances for treatment or prevention of insufficient longitudinal growth of eye(hypermetropia) or excessive longitudinal growth of eye(myopia); involves measurement of effect on retinal pigment epithelium RYR1, ATP2A2, ATP2A1 TYMP 3487/4885GDA 2944/4885
US-20180289815-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS HACD3, ALG1, HACD2 TYMP 1741/4885GDA 2595/4885
US-20220257770-A1 HYDROPHOBIC HIGHLY BRANCHED CARBOHYDRATE POLYMERS HACD3, ALG1, HACD2 TYMP 1741/4885GDA 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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