SCHEMBL6742216

SCHEMBL6742216

CCc1scc(Cl)c1S(=O)(=O)N=C=S

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026666 0.77 POLB (0.40)
SCHEMBL6734186 0.62 GABRA1 (0.46) GABRA1GABRB2
SCHEMBL7031788 0.62 COMT (0.34)
SCHEMBL28118419 0.62
SCHEMBL7026714 0.61 MAPT (0.39)
SCHEMBL21737591 0.61
SCHEMBL7463317 0.59 GLA (0.31)
SCHEMBL5414986 0.59 MAPT (0.35)
SCHEMBL14404559 0.57 CTRC (0.30)
SCHEMBL6432730 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686478-B2 NOVEL INTERMEDIATES FOR THEIR PREPARATION; HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 US disclosed
US-20030171595-A1 Thienylsulphonylamino(thio)carbonyl compounds MULLER KLAUS-HELMUT (DE) 2003-09-11 US disclosed
US-6566536-B2 Herbicides BAYER AKTIENGESELLSCHAFT (DE) 2003-05-20 US disclosed
US-20030004354-A1 Thienylsulphonylamino(thio)carbonyl compounds MULLER KLAUS-HELMUT (DE) 2003-01-02 US disclosed
US-6383988-B1 HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-07 US disclosed
EP-0942908-B1 THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS BAYER AG (DE) 2002-02-13 EP disclosed
EP-0942908-A1 THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS BAYER AG (DE) 1999-09-22 EP disclosed
WO-1998024787-A1 THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171595-A1 Thienylsulphonylamino(thio)carbonyl compounds CBR3, CBR1, QSOX1 GABRA1 3483/4885GABRB2 3756/4885
US-20030004354-A1 Thienylsulphonylamino(thio)carbonyl compounds CBR3, CBR1, QSOX1 GABRA1 3483/4885GABRB2 3756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.