SCHEMBL674238

SCHEMBL674238

CN(SC(F)(Cl)Cl)S(=O)(=O)N(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 6/20 0.41
KDM4E B2RXH2 1/20 0.41
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
NR1H2 P55055 5/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36
KCNJ11 Q14654 1/20 0.36
KCNJ8 Q15842 1/20 0.36
PGR P06401 1/20 0.35
NR1I2 O75469 1/20 0.35
USP30 Q70CQ3 1/20 0.35
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673951 0.86 MAPT (0.45) NR1H3KDM4ECA12CA9MCOLN3
SCHEMBL8722316 0.78 NR1H3 (0.44) NR1H3KDM4ECA12CA9MCOLN3
Dichlofluanid SCHEMBL20684 0.77 POLB (0.38) NR1H3KDM4ECA12CA9NR1H2
Dichlofluanid SCHEMBL13858863 0.77 POLB (0.38) NR1H3KDM4ECA12CA9NR1H2
Dichlofluanid SCHEMBL27504391 0.76 POLB (0.37) NR1H3KDM4ECA12CA9NR1H2
SCHEMBL11017055 0.74 CA12 (0.39) NR1H3KDM4ECA12CA9MCOLN3
SCHEMBL25137428 0.74 CA12 (0.55) NR1H3KDM4ECA12CA9MCOLN3
SCHEMBL8338196 0.73 CA12 (0.41) NR1H3KDM4ECA12CA9MCOLN3
SCHEMBL10441615 0.73 HPGD (0.42) CA12CA9MEN1ALDH1A1KMT2A
SCHEMBL9295422 0.73 NR1H3 (0.40) NR1H3KDM4ECA12CA9MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10858521-B2 Antifouling coating compositions, antifouling coating films, antifouling substrates, methods for producing antifouling substrates, and methods of storing antifouling coating compositions CHUGOKU MARINE PAINTS, LTD. (JP) 2020-12-08 US claimed
EP-3299427-B1 ANTIFOULING COATING MATERIAL COMPOSITION, ANTIFOULING COATING FILM, ANTIFOULING BASE, METHOD FOR PRODUCING ANTIFOULING BASE, AND METHOD FOR STORING ANTIFOULING COATING MATERIAL COMPOSITION CHUGOKU MARINE PAINTS (JP) 2020-06-17 EP claimed
US-20180105703-A1 ANTIFOULING COATING COMPOSITIONS, ANTIFOULING COATING FILMS, ANTIFOULING SUBSTRATES, METHODS FOR PRODUCING ANTIFOULING SUBSTRATES, AND METHODS OF STORING ANTIFOULING COATING COMPOSITIONS CHUGOKU MARINE PAINTS, LTD. (JP) 2018-04-19 US claimed
EP-2551309-B1 ANTIFOULING COATING COMPOSITION AND USE FOR SAME CHUGOKU MARINE PAINTS (JP) 2017-05-17 EP claimed
US-8840910-B2 Antifouling coating composition and uses of the same CHUGOKU MARINE PAINTS, LTD. (JP) 2014-09-23 US claimed
US-20130045264-A1 ANTIFOULING COATING COMPOSITION AND USES OF THE SAME CHUGOKU MARINE PAINTS, LTD. (JP) 2013-02-21 US claimed
EP-2551309-A1 ANTIFOULING COATING COMPOSITION AND USE FOR SAME Chugoku Marine Paints, Ltd. (JP) 2013-01-30 EP claimed
US-8153705-B2 Silyl esters, their use in binder systems and paint compositions and a process for production thereof SIGMAKALON B.V. (NL) 2012-04-10 US claimed
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 EP claimed
US-5470586-A Antifouling coating and method for using same DUKE UNIVERSITY (US) 1995-11-28 US claimed
US-5334389-A Antifouling coating and method for using same DUKE UNIVERSITY (US) 1994-08-02 US claimed
US-5314932-A Bufalin derivative, underwater surfaces DUKE UNIVERSITY (US) 1994-05-24 US claimed
WO-1994008904-A1 ANTIFOULING COATING COMPOSITION AND METHOD DUKE UNIVERSITY (US) 1994-04-28 WO claimed
WO-1993024008-A2 MIXTURES OF ACTIVE ANTI-MICROBIAL SUBSTANCES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1993-12-09 WO claimed
US-5259701-A Antifouling coating composition comprising furan compounds, method for protecting aquatic structures, and articles protected against fouling organisms ROHM AND HAAS COMPANY (US) 1993-11-09 US claimed
US-5252630-A Marine microorganisms DUKE UNIVERSITY (US) 1993-10-12 US claimed
US-5248221-A Antifouling coating composition comprising lactone compounds, method for protecting aquatic structures, and articles protected against fouling organisms ROHM AND HAAS COMPANY (US) 1993-09-28 US claimed
EP-0051198-A1 Method for the preparation of 2-halo-3-sulfonyl-acrylonitriles and their use BAYER AG (DE) 1982-05-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045264-A1 ANTIFOULING COATING COMPOSITION AND USES OF THE SAME ADRB2, OPRM1, CHRM2 NR1H3 366/4885KDM4E 2556/4885CA12 48/4885
US-10858521-B2 Antifouling coating compositions, antifouling coating films, antifouling substrates, methods for producing antifouling substrates, and methods of storing antifouling coating compositions ITGA5, SIGMAR1, ITGB6 NR1H3 42/4885KDM4E 784/4885CA12 2416/4885
US-20180105703-A1 ANTIFOULING COATING COMPOSITIONS, ANTIFOULING COATING FILMS, ANTIFOULING SUBSTRATES, METHODS FOR PRODUCING ANTIFOULING SUBSTRATES, AND METHODS OF STORING ANTIFOULING COATING COMPOSITIONS ITGA5, SIGMAR1, ITGB6 NR1H3 42/4885KDM4E 784/4885CA12 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.