Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102121 | 0.80 | TLR8 (0.47) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL6128303 | 0.78 | TLR8 (0.69) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL3751497 | 0.78 | NUDT1 (0.55) | AURKAPDPK1TGFBR1AURKBNUDT1 | |
| SCHEMBL1318375 | 0.77 | CYP2D6 (0.64) | TLR8AURKAPDPK1TGFBR1AURKB | |
| Hydrochloric Acid SCHEMBL1900898 | 0.76 | TLR8 (0.44) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL9182270 | 0.74 | NUDT1 (0.66) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL763729 | 0.74 | TLR8 (0.42) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL20161606 | 0.74 | RAB9A (0.44) | TLR8AURKAPDPK1TGFBR1AURKB | |
| SCHEMBL6898924 | 0.71 | — | — | |
| SCHEMBL28736407 | 0.70 | CYP1A2 (0.64) | TLR8AURKAPDPK1TGFBR1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040260038-A1 | Maleic acid derivative and curable composition containing the same | TEH YOKOHAMA RUBBER CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |