Cinnamic Acid

Cinnamic Acid

SCHEMBL6742986

Nc1ccc(C(=O)O)cc1.O=C(O)/C=C/c1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 6/20 0.70
HCAR2 Q8TDS4 2/20 0.66
HDAC3 O15379 1/20 0.66
TNKS O95271 1/20 0.66
HDAC4 P56524 1/20 0.66
HDAC1 Q13547 1/20 0.66
HDAC7 Q8WUI4 1/20 0.66
HDAC2 Q92769 1/20 0.66
HDAC10 Q969S8 1/20 0.66
HDAC11 Q96DB2 1/20 0.66
HDAC8 Q9BY41 1/20 0.66
TNKS2 Q9H2K2 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
HDAC9 Q9UKV0 1/20 0.66
HDAC5 Q9UQL6 1/20 0.66
NPSR1 Q6W5P4 1/20 0.57
MAOB P27338 3/20 0.52
CYP19A1 P11511 2/20 0.52
MAOA P21397 2/20 0.52
MAPT P10636 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Acid SCHEMBL9102682 1.00 CYP1B1 (0.70) CYP1B1HCAR2HDAC3TNKSHDAC4
Cinnamic Acid SCHEMBL10803545 0.87 HCAR2 (0.79) CYP1B1HCAR2HDAC3TNKSHDAC4
Cinnamic Acid SCHEMBL10996900 0.87 HCAR2 (0.79) CYP1B1HCAR2HDAC3TNKSHDAC4
Cinnamic Acid SCHEMBL11878212 0.85 HCAR2 (0.76) CYP1B1HCAR2HDAC3TNKSHDAC4
Cinnamic Acid SCHEMBL11878207 0.85 HCAR2 (0.76) CYP1B1HCAR2HDAC3TNKSHDAC4
Benzene SCHEMBL6912055 0.85 HCAR2 (0.68) CYP1B1HCAR2HDAC3TNKSHDAC4
Cinnamic Acid SCHEMBL7261608 0.85 HCAR2 (0.63) CYP1B1HCAR2HDAC3TNKSHDAC4
SCHEMBL70241 0.83 HCAR2 (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL143559 0.83 CA12 (0.65) CYP1B1HCAR2HDAC3TNKSHDAC4
SCHEMBL1001682 0.83 CA12 (0.65) CYP1B1HCAR2HDAC3TNKSHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696069-B2 ORGANIC SULFONATE, PHOSPHATE OR SULFATE UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-20020041890-A1 Skin care cosmetic compositions containing phosphates and/or sulfates of branched alcohols and/or ethoxylates thereof UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-04-11 US disclosed
WO-2002002072-A2 SKIN CARE COSMETIC COMPOSITIONS CONTAINING PHOSPHATES AND/OR SULFATES OF BRANCHED ALCOHOLS AND/OR ETHOXYLATES THEREOF UNILEVER PLC (GB) 2002-01-10 WO disclosed
EP-0713383-A1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1996-05-29 EP disclosed
WO-1995005150-A1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020041890-A1 Skin care cosmetic compositions containing phosphates and/or sulfates of branched alcohols and/or ethoxylates thereof CUTA, EBP, EYA3 CYP1B1 3550/4885HCAR2 3356/4885HDAC3 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.