Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.50 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741690 | 0.84 | ITGA4 (0.43) | ITGB1ITGA4 | |
| SCHEMBL6740498 | 0.84 | ITGB1 (0.50) | ITGB1ITGA4 | |
| SCHEMBL6743023 | 0.75 | ITGB1 (0.46) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL15147586 | 0.73 | ITGB1 (0.64) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL15147585 | 0.73 | ITGB1 (0.64) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6512179 | 0.73 | KMT2A (0.64) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6627877 | 0.73 | ITGB1 (0.88) | ITGB1ITGA4 | |
| SCHEMBL6639157 | 0.72 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6637068 | 0.72 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL27519787 | 0.72 | ITGB1 (0.80) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685617-B1 | 4-(((-1-CARBOXY-2-(4-((2,6-DICHLOROBENZOYL)AMINE)PHENYL)ETHYL) AMINO)CARBONYL)-3-OXO-3-THIAZOLIDINEBUTANOIC ACID, USED AS ANTAGONISTS FOR CELLULAR ADHESION MOLECULES, AND ADMINISTERED AS ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |