SCHEMBL6743138

SCHEMBL6743138

O=S(=O)(O)c1cccc2cccc(OS(=O)(=O)c3ccccc3)c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.51
METAP1 P53582 1/20 0.51
TTR P02766 1/20 0.49
FABP4 P15090 1/20 0.49
CCNA2 P20248 1/20 0.49
CDK2 P24941 1/20 0.49
MAPK14 Q16539 1/20 0.49
NR4A1 P22736 1/20 0.48
ALDH1A1 P00352 3/20 0.46
FABP1 P07148 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
HSD11B1 P28845 1/20 0.41
HSD17B3 P37058 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482422 0.87 KMT2A (0.53) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL4079124 0.86 KMT2A (0.52) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL6742392 0.86 HTR6 (0.46) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL6740263 0.80 MEN1 (0.51) METAP2METAP1TTRALDH1A1MEN1
SCHEMBL9628182 0.78 CDK2 (0.51) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL11307787 0.76 AURKA (0.56) METAP2METAP1TTRNR4A1ALDH1A1
SCHEMBL6743103 0.76 LMNA (0.46) METAP2METAP1ALDH1A1MEN1KMT2A
SCHEMBL9054922 0.76 TTR (0.41) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL6745151 0.76 LMNA (0.46) METAP2METAP1ALDH1A1MEN1KMT2A
SCHEMBL12545615 0.76 TTR (0.47) TTRFABP4CCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6692893-B2 ONIUM SALTS OF ARYLSULFONYLOXYNAPHTHALENESULFONATE ANIONS WITH IODONIUM OR SULFONIUM CATIONS; USE IN DEEP ULTRAVIOLET LITHOGRAPHY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-02-17 US disclosed
US-20020076643-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020076643-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process PNN, PI4K2B, PI4K2A METAP2 1511/4885METAP1 2936/4885TTR 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.