P-Cymene

P-Cymene

SCHEMBL7517875

Cc1ccc(C(C)C)cc1.N[C@H](c1ccccc1)[C@H](NS(=O)(=O)c1ccc(F)cc1)c1ccccc1.[Ru]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
NPSR1 Q6W5P4 4/20 0.46
HTT P42858 3/20 0.44
LMNA P02545 3/20 0.44
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.40
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP7 P09237 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
HPN P05981 2/20 0.39
PLAU P00749 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cymene SCHEMBL6740633 1.00 ALDH1A1 (0.46) ALDH1A1NPSR1HTTLMNASLC1A3
P-Cymene SCHEMBL2240125 0.94 ALDH1A1 (0.50) ALDH1A1NPSR1HTTLMNASLC1A3
P-Cymene SCHEMBL3579869 0.94 ALDH1A1 (0.50) ALDH1A1NPSR1HTTLMNASLC1A3
P-Cymene SCHEMBL6743208 0.92 NPSR1 (0.47) ALDH1A1NPSR1HTTLMNASLC1A3
P-Cymene SCHEMBL7527837 0.92 NPSR1 (0.47) ALDH1A1NPSR1HTTLMNASLC1A3
P-Cymene SCHEMBL3341178 0.91 NPSR1 (0.49) ALDH1A1NPSR1HTTLMNASLC1A3
P-Xylene SCHEMBL5421492 0.88 ALDH1A1 (0.52) ALDH1A1NPSR1HTTLMNASLC1A3
Benzene SCHEMBL3854289 0.88 ALDH1A1 (0.52) ALDH1A1NPSR1HTTLMNASLC1A3
SCHEMBL3342411 0.88 ALDH1A1 (0.52) ALDH1A1NPSR1HTTLMNASLC1A3
P-Xylene SCHEMBL5424500 0.88 ALDH1A1 (0.52) ALDH1A1NPSR1HTTLMNASLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495701-B1 THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-12-17 US disclosed
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed