Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744671 | 0.89 | KDM4E (0.46) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL6747696 | 0.81 | KDM4E (0.69) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL6747698 | 0.78 | HPGDS (0.43) | KDM4ELMNATP53CCR1CCR5 | |
| Terpyridine SCHEMBL57442 | 0.76 | KDM4E (1.00) | KDM4ELMNATP53CCR1CCR5 | |
| Terpyridine SCHEMBL29357603 | 0.76 | KDM4E (1.00) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL7964803 | 0.76 | KDM4E (1.00) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL30172832 | 0.76 | KDM4E (1.00) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL6744259 | 0.76 | KDM4E (0.56) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL4949169 | 0.75 | KDM4E (0.60) | KDM4ELMNATP53CCR1CCR5 | |
| SCHEMBL6745925 | 0.74 | KDM4E (0.58) | KDM4ELMNATP53CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696182-B2 | HIGH PERFORMANCE DIPYRIDYL THIOPHENE OR DIPYRIDYL THIOPHENE DIOXIDE ELECTRON TRANSPORT MATERIALS WHICH WHEN EMPLOYED CAN GIVE LOW-VOLTAGE, HIGH EFFICIENCY ORGANIC ELECTROLUMINESCENT DEVICES | CHISSO CORPORATION (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-1186605-B1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORP (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-20020034658-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORPORATION (JP) | 2002-03-21 | — | — | US | disclosed |
| EP-1186605-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020034658-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | LAGE3, MAL2, ELF3 | KDM4E 276/4885LMNA 2640/4885TP53 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.