Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746727 | 0.89 | PTGS2 (0.47) | PTGS2KDM4E | |
| SCHEMBL6743170 | 0.88 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL6747140 | 0.88 | PTGS2 (0.36) | PTGS2 | |
| SCHEMBL6744855 | 0.88 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL6744389 | 0.88 | PTGS2 (0.35) | PTGS2CCR2 | |
| SCHEMBL6746755 | 0.87 | SCN9A (0.44) | PTGS2 | |
| SCHEMBL6745201 | 0.86 | ACLY (0.43) | PTGS2 | |
| SCHEMBL6747114 | 0.86 | RAB9A (0.40) | PTGS2CCR2RAB9AF10 | |
| SCHEMBL6746854 | 0.86 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL6743703 | 0.85 | PTGS2 (0.52) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |