Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133697 | 0.85 | LMNA (0.48) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL1260714 | 0.82 | MAPT (0.56) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL31238640 | 0.82 | MAPT (0.56) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL29083889 | 0.79 | MAPT (0.58) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL31294858 | 0.78 | MAPT (0.53) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL15599566 | 0.76 | MAPT (0.54) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL30194888 | 0.76 | MAPT (0.54) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL16388846 | 0.76 | LMNA (0.50) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL2490968 | 0.74 | OPRM1 (0.59) | MAPTLMNAKDM4EHCRTR1ALDH1A1 | |
| SCHEMBL30548955 | 0.74 | OPRM1 (0.59) | MAPTLMNAKDM4EHCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138230-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | ANDREANA TONJA LYNN (US) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138230-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | CNR1, DRD2, CNR2 | MAPT 2926/4885LMNA 4160/4885KDM4E 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.