Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MPI | P34949 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744652 | 1.00 | GAA (0.71) | GAAKDM4EL3MBTL1LMNAMPI | |
| Hydrochloric Acid SCHEMBL6843997 | 0.98 | GAA (0.69) | GAAKDM4EL3MBTL1LMNAMPI | |
| Hydrochloric Acid SCHEMBL6843998 | 0.98 | GAA (0.69) | GAAKDM4EL3MBTL1LMNAMPI | |
| SCHEMBL6746441 | 0.86 | KDM4E (0.70) | GAAKDM4EL3MBTL1LMNAMPI | |
| SCHEMBL16224301 | 0.86 | NOX4 (0.70) | GAAKDM4EL3MBTL1LMNAMPI | |
| SCHEMBL29483210 | 0.86 | KDM4E (0.70) | GAAKDM4EL3MBTL1LMNAMPI | |
| SCHEMBL6746442 | 0.86 | KDM4E (0.70) | GAAKDM4EL3MBTL1LMNAMPI | |
| Hydrochloric Acid SCHEMBL6746502 | 0.85 | KDM4E (0.68) | GAAKDM4EL3MBTL1LMNAMPI | |
| SCHEMBL6740035 | 0.85 | NTRK1 (0.54) | GAAKDM4EL3MBTL1LMNAMPI | |
| Hydrochloric Acid SCHEMBL17560991 | 0.85 | NOX4 (0.68) | GAAKDM4EL3MBTL1LMNAMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186993-A1 | Anti-malarial compounds, compositions and methods | KENNETH S. WARREN INSTITUTE | 2003-10-02 | — | — | US | claimed |
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | METHODS PRODUCTS PBC | 2022-01-20 | — | — | US | disclosed |
| US-6689777-B2 | DEPOLYMERIZING HEMOZOIN USING 2-IMINO-NAPHTHO(1,2-D)THIAZOL-5-OL DERIVATIVES | KENNETH S. WARREN INSTITUTE | 2004-02-10 | — | — | US | disclosed |
| US-20030186993-A1 | Anti-malarial compounds, compositions and methods | KENNETH S. WARREN INSTITUTE | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186993-A1 | Anti-malarial compounds, compositions and methods | TYR, CRYZ, RHOT2 | GAA 260/4885KDM4E 1240/4885L3MBTL1 1936/4885 |
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | PCNA, POLM, MUS81 | GAA 729/4885KDM4E 3334/4885L3MBTL1 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.