Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592722 | 0.89 | ACHE (0.49) | ACHEPOLBKMT2ABCHEMEN1 | |
| Iodide SCHEMBL18497004 | 0.87 | ACHE (0.51) | ACHEPOLBKMT2ABCHEMEN1 | |
| Hydrochloric Acid SCHEMBL9205826 | 0.87 | ACHE (0.47) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL2824489 | 0.85 | ACHE (0.44) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL34461983 | 0.85 | ACHE (0.44) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL6743438 | 0.79 | CYP2A6 (0.34) | ACHEKMT2AMEN1LMNAMAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL31472680 | 0.79 | KCNH2 (0.41) | ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL4497025 | 0.79 | KCNH2 (0.41) | ACHE | |
| SCHEMBL11092159 | 0.72 | ACHE (0.35) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL7561304 | 0.72 | ACHE (0.44) | ACHEPOLBKMT2ABCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |