Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824489 | 1.00 | ACHE (0.44) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL4592722 | 0.92 | ACHE (0.49) | ACHEPOLBKMT2ABCHEMEN1 | |
| Hydrochloric Acid SCHEMBL9205826 | 0.90 | ACHE (0.47) | ACHEPOLBKMT2ABCHEMEN1 | |
| Iodide SCHEMBL18497004 | 0.90 | ACHE (0.51) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL6744860 | 0.85 | ACHE (0.42) | ACHEPOLBKMT2ABCHEMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4497025 | 0.79 | KCNH2 (0.41) | ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL31472680 | 0.79 | KCNH2 (0.41) | ACHE | |
| SCHEMBL6331349 | 0.78 | ACHE (0.44) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL6337322 | 0.78 | CYP2A6 (0.36) | ACHEKMT2AMEN1LMNAMAPT | |
| SCHEMBL4625061 | 0.77 | MEN1 (0.40) | ACHEPOLBKMT2ABCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12599577-B2 | Thermoresponsive gel eye drop for ocular delivery of cysteamine | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2026-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12599577-B2 | Thermoresponsive gel eye drop for ocular delivery of cysteamine | CRYAA, PKD2, SLC7A11 | ACHE 2935/4885POLB 4384/4885KMT2A 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.