Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361778 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1L3MBTL1TP53 | |
| SCHEMBL22618507 | 0.87 | ALDH1A1 (0.55) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5166388 | 0.80 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL4453106 | 0.72 | NPC1 (0.37) | TSHRTDP1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31437603 | 0.71 | RAB9A (0.51) | TDP1ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL7775643 | 0.71 | TDP1 (0.61) | TSHRTDP1ALDH1A1L3MBTL1TP53 | |
| SCHEMBL7699953 | 0.71 | NPC1 (0.47) | ALDH1A1TP53CYP3A4NPC1RAB9A | |
| SCHEMBL29031120 | 0.71 | RAB9A (0.51) | TDP1ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL13121650 | 0.71 | GABRA1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9175550 | 0.70 | NPC1 (0.44) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762250-B2 | TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-07-13 | — | — | US | disclosed |
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20040054116-A1 | Polycarbonate resin composition | MITSUBISHI ENGINEERING-PLASTICS CORPORATION | 2004-03-18 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |