SCHEMBL6745155

SCHEMBL6745155

CCc1cccc(Oc2cccc(CC)c2N)c1N

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 1/20 0.38
SLC6A4 P31645 4/20 0.36
SLC6A2 P23975 3/20 0.36
SLC6A3 Q01959 3/20 0.36
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28156480 0.87 HRH1 (0.51) ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL5829892 0.85 IDO1 (0.47) GABRA1GABRB2MAPTL3MBTL1ALDH1A1
SCHEMBL11139017 0.83 L3MBTL1 (0.56) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL1332031 0.81 GABRA1 (0.55) GABRA1GABRB2MAPTALDH1A1
SCHEMBL262868 0.81 GABRA1 (0.55) GABRA1GABRB2MAPTALDH1A1
SCHEMBL11868776 0.80 MCHR1 (0.49) MAPTL3MBTL1NPSR1ALDH1A1HPGD
SCHEMBL27645024 0.80 PPARG (0.50) GABRA1GABRB2ALDH1A1HPGD
SCHEMBL17887315 0.80 MCHR1 (0.44) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL27595685 0.79 IDO1 (0.41) MAPTALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL10665768 0.79 CYP1A2 (0.58) MAPTL3MBTL1NPSR1ALDH1A1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296540-B1 DISPLAY TORAY INDUSTRIES (JP) 2019-10-16 EP disclosed
US-6696112-B2 POSITIVE-TYPE, PHOTOSENSITIVITY; FLAT PANEL DISPLAYS TORAY INDUSTRIES, INC. (JP) 2004-02-24 US disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed