Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79617 | 0.80 | S100A4 (0.56) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL10587103 | 0.78 | S100A4 (0.54) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL4668872 | 0.78 | S100A4 (0.54) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL31376098 | 0.78 | S100A4 (0.54) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL6745161 | 0.76 | TDP1 (0.59) | S100A4ALOX15TDP1KDM4EKMT2A | |
| SCHEMBL17195907 | 0.73 | S100A4 (0.48) | S100A4PPOXCA12CA1CA2 | |
| Bicarbonate SCHEMBL9337931 | 0.70 | CA1 (0.50) | S100A4PPOXCA12CA1CA2 | |
| Bicarbonate SCHEMBL9337919 | 0.70 | CA1 (0.50) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL20932736 | 0.69 | PPOX (0.48) | S100A4PPOXCA12CA1CA2 | |
| SCHEMBL28915467 | 0.66 | KDM4E (0.67) | S100A4TDP1KDM4EKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040225136-A1 | Process for the preparation of 5-formylphthalide | H. LUNDBECK A/S (DK) | 2004-11-11 | — | — | US | disclosed |
| WO-2003011847-A1 | PROCESS FOR THE PREPARATION OF 5-FORMYLPHTHALIDE | INFOSINT SA (CH) | 2003-02-13 | — | — | WO | disclosed |
| EP-1281708-A1 | Process for the preparation of 5-Formylphthalide | INFOSINT SA (CH) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225136-A1 | Process for the preparation of 5-formylphthalide | HTR5A, TPH1, HTR6 | S100A4 1458/4885PPOX 192/4885CA12 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.