SCHEMBL6745230

SCHEMBL6745230

C/C(=C/C(=O)OC(=O)/C=C\C(N)=O)C(=O)OC(=O)/C=C\C(N)=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2408879 0.82 HCAR2 (0.45) KEAP1NFE2L2HCAR2
SCHEMBL9297271 0.80 ALDH1A1 (0.31)
SCHEMBL2382928 0.78 HCAR2 (0.38) KEAP1NFE2L2HCAR2
SCHEMBL3839110 0.78 HCAR2 (0.38) KEAP1NFE2L2HCAR2
SCHEMBL4390645 0.76 ALDH1A1 (0.36) HCAR2
SCHEMBL21114351 0.75 MEN1 (0.31)
SCHEMBL5670909 0.75 HCAR2 (0.39) KEAP1NFE2L2HCAR2
SCHEMBL28281917 0.74 ALDH1A1 (0.50) KEAP1NFE2L2HCAR2
SCHEMBL27864576 0.74 ALDH1A1 (0.36)
SCHEMBL6745227 0.73 TSHR (0.35) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6692825-B2 SUPERABSORBENT FIBERS; DISPOSABLE PRODUCTS KIMBERLY-CLARK WORLDWIDE, INC. 2004-02-17 US disclosed
US-20020164914-A1 Synthetic fiber nonwoven web and method KIMBERLY-CLARK WORLDWIDE, INC. 2002-11-07 US disclosed