SCHEMBL2382928

SCHEMBL2382928

NC(=O)/C=C\C(=O)OC(=O)/C=C\C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
MAPT P10636 2/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
DDAH1 O94760 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839110 1.00 HCAR2 (0.38) HCAR2KEAP1NFE2L2ALDH1A1TSHR
SCHEMBL11029234 0.88 KEAP1 (0.35) HCAR2KEAP1NFE2L2ALDH1A1TSHR
Glycerin SCHEMBL20660156 0.82 ALDH1A1 (0.38) ALDH1A1
SCHEMBL23295798 0.81 HCAR2 (0.38) HCAR2KEAP1NFE2L2ALDH1A1TSHR
SCHEMBL558370 0.80
SCHEMBL245241 0.79
SCHEMBL156118 0.79
SCHEMBL156117 0.79
SCHEMBL7193583 0.79
SCHEMBL6745230 0.78 KEAP1 (0.30) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909753-A Sulfonate compositions and preservative compositions comprising the same 斯凯孚公司 2020-11-10 CN claimed
CN-110511172-A The method that loaded catalyst catalysis prepares bis- (3- ethyl -5- methyl -4- dimaleoyl imino benzene) methane HAISO TECH CO LTD 2019-11-29 CN claimed
US-20030144393-A1 Functionalised silane-based compounds, methods for producing them and their use in the area of rubber materials RHODIA CHIMIE (FR) 2003-07-31 US claimed
EP-1242429-B1 FUNCTIONALISED SILANE-BASED COMPOUNDS, METHODS FOR PRODUCING THEM AND THEIR USE IN THE AREA OF RUBBER MATERIALS RHODIA CHIMIE SA (FR) 2003-07-02 EP claimed
CN-116270495-A Degradable double-drug-loaded nanoparticle and preparation method thereof 滨州医学院 2023-06-23 CN disclosed
CN-113811580-B Preservative composition 斯凯孚公司 2023-01-24 CN disclosed
CN-113811580-A Preservative composition 斯凯孚公司 2021-12-17 CN disclosed
US-10844303-B1 Method for the production of fuel oil CAMPBELL GALE (US) 2020-11-24 US disclosed
CN-111909753-A Sulfonate compositions and preservative compositions comprising the same 斯凯孚公司 2020-11-10 CN disclosed
CN-110511172-A The method that loaded catalyst catalysis prepares bis- (3- ethyl -5- methyl -4- dimaleoyl imino benzene) methane HAISO TECH CO LTD 2019-11-29 CN disclosed
EP-3475958-A1 ELECTRICALLY CONDUCTIVE SHAPED BODY WITH A POSITIVE TEMPERATURE COEFFICIENT Thüringisches Institut für Textil- und Kunststoff-Forschung e.V. (DE) 2019-05-01 EP disclosed
US-10227541-B2 Lubricating oil composition for transmissions JX NIPPON OIL & ENERGY CORPORATION (JP) 2019-03-12 US disclosed
EP-1279073-A1 TONER FOR ELECTROSTATICALLY CHARGED IMAGE DEVELOPMENT Ticona GmbH (DE) 2003-01-29 EP disclosed
US-20020119896-A1 Lubricant compositions NIPPON MITSUBISHI OIL CORPORATION 2002-08-29 US disclosed
EP-1195427-A2 Lubricant compositions suitable as engine oils Nippon Mitsubishi Oil Corporation (JP) 2002-04-10 EP disclosed
WO-2001084248-A1 TONER FOR ELECTROSTATICALLY CHARGED IMAGE DEVELOPMENT TICONA GMBH (DE) 2001-11-08 WO disclosed
US-6242393-B1 NAPHTHENIC HYDROCARBONS, CARBOXYLATES OR CARBONATES FOR TRACTION NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-06-05 US disclosed
US-6191330-B1 SATURATED POLYCYCLIC HYDROCARBONS; AUTOMATIC TRANSMISSION NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-02-20 US disclosed
EP-0989177-A1 Traction drive fluid Nippon Mitsubishi Oil Corporation (JP) 2000-03-29 EP disclosed
EP-0949319-A2 Traction drive fluid Nippon Mitsubishi Oil Corporation (JP) 1999-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144393-A1 Functionalised silane-based compounds, methods for producing them and their use in the area of rubber materials RIF1, H1-2, RER1 HCAR2 491/4885KEAP1 1683/4885NFE2L2 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.