Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2382928 | 1.00 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL11029234 | 0.88 | KEAP1 (0.35) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| Glycerin SCHEMBL20660156 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL23295798 | 0.81 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL558370 | 0.80 | — | — | |
| SCHEMBL245241 | 0.79 | — | — | |
| SCHEMBL156118 | 0.79 | — | — | |
| SCHEMBL156117 | 0.79 | — | — | |
| SCHEMBL7193583 | 0.79 | — | — | |
| SCHEMBL6745230 | 0.78 | KEAP1 (0.30) | HCAR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125918-A2 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | Dow Global Technologies Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079784-A2 | FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-07-03 | — | — | WO | disclosed |