SCHEMBL6745440

SCHEMBL6745440

CCOC(=O)C(F)(F)CC(I)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.38
PKM P14618 3/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 2/20 0.32
HIF1A Q16665 1/20 0.32
HTT P42858 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921940 0.82 MAPT (0.34) MMP8ALDH1A1KDM4EKMT2APOLB
SCHEMBL7928035 0.80 POLB (0.33) MMP8KDM4EKMT2APOLBNPSR1
SCHEMBL25972548 0.79 MMP8 (0.36) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL21622345 0.79 MMP8 (0.36) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL10290301 0.79 MMP8 (0.53) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL22490101 0.76 MMP8 (0.42) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL8413326 0.76 MMP8 (0.42) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL8413328 0.76 MMP8 (0.42) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL20654571 0.74 MMP8 (0.38) MMP8PKMALDH1A1KDM4EMEN1
SCHEMBL23175267 0.74 ALDH1A1 (0.40) MMP8PKMALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208083-B1 LOW TEMPERATURE INITIATORS FOR FLUOROOLEFIN POLYMERIZATION DU PONT (US) 2004-11-03 EP disclosed
US-6700023-B1 FLUOROALKYL DIACYL PEROXIDES E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-02 US disclosed
CN-1371363-A Low temperaure initators for fluoroolefin polymerization DU PONT (US) 2002-09-25 CN disclosed
EP-1208083-A1 LOW TEMPERATURE INITIATORS FOR FLUOROOLEFIN POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-05-29 EP disclosed
WO-2001016100-A1 LOW TEMPERATURE INITIATORS FOR FLUOROOLEFIN POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-08 WO disclosed