Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413326 | 1.00 | MMP8 (0.42) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL10290301 | 0.84 | MMP8 (0.53) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL22490101 | 0.81 | MMP8 (0.42) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL20654571 | 0.79 | MMP8 (0.38) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL4138413 | 0.78 | MMP8 (0.47) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL24363762 | 0.77 | KMT2A (0.42) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL23907130 | 0.76 | MMP8 (0.45) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL6745440 | 0.76 | MMP8 (0.38) | MMP8ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL20413839 | 0.75 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL1681615 | 0.74 | CYP4F2 (0.44) | MMP8ALDH1A1PKMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690049-B1 | Agent for treating hepato biliary diseases | R TECH UENO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5739161-A | PROSTAGLANDINS; DIARRHEA SIDE EFFECT REDUCTION | R-TECH UENO, LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0690049-A2 | Agent for treating hepato biliary diseases | R-TECH UENO LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |