Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 16/20 | 0.66 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750559 | 0.91 | ICAM1 (0.63) | ICAM1FAAH | |
| SCHEMBL6751985 | 0.80 | ICAM1 (0.47) | ICAM1 | |
| SCHEMBL7149885 | 0.73 | ICAM1 (0.53) | ICAM1FAAH | |
| SCHEMBL7173360 | 0.71 | ICAM1 (0.45) | ICAM1 | |
| SCHEMBL6745827 | 0.71 | HDAC6 (0.36) | ICAM1 | |
| SCHEMBL6747212 | 0.68 | ICAM1 (0.42) | ICAM1FAAH | |
| SCHEMBL6746486 | 0.68 | ICAM1 (0.42) | ICAM1FAAH | |
| SCHEMBL8317486 | 0.67 | ICAM1 (0.47) | ICAM1 | |
| SCHEMBL6747160 | 0.67 | NOX1 (0.37) | ICAM1 | |
| SCHEMBL7180856 | 0.66 | ICAM1 (0.42) | ICAM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | ICAM1 412/4885FAAH 604/4885ACHE 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.