Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 8/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752117 | 0.85 | ICAM1 (0.45) | ICAM1FAAHMEN1POLBKMT2A | |
| SCHEMBL7149891 | 0.83 | ALDH1A1 (0.35) | ICAM1FAAHMEN1POLBKMT2A | |
| SCHEMBL6752121 | 0.80 | ICAM1 (0.35) | ICAM1FAAHMEN1POLBKMT2A | |
| SCHEMBL6750559 | 0.75 | ICAM1 (0.63) | ICAM1FAAHCHRM4 | |
| SCHEMBL6745545 | 0.73 | ICAM1 (0.66) | ICAM1FAAH | |
| SCHEMBL6746486 | 0.70 | ICAM1 (0.42) | ICAM1FAAH | |
| SCHEMBL6749892 | 0.70 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8522768 | 0.69 | ICAM1 (0.36) | ICAM1KDM4EALDH1A1 | |
| SCHEMBL6751892 | 0.68 | ICAM1 (0.43) | ICAM1KDM4EALDH1A1 | |
| SCHEMBL6751888 | 0.68 | ICAM1 (0.43) | ICAM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |