SCHEMBL6745618

SCHEMBL6745618

NC(C(c1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.58
F2 P00734 1/20 0.58
HTR2A P28223 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TACR1 P25103 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872345 0.84 ADRA2A (0.48) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL17504544 0.84 ADRA2A (0.54) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL1168889 0.84 ADRA2A (0.48) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL790467 0.81 DPP4 (0.58) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL448348 0.79 DPP4 (0.53) DPP4F2HTR2ATAAR1LMNA
SCHEMBL1168297 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1143202 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1143444 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1168170 0.77 ADRA2A (0.58) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL4451068 0.77 DPP4 (0.52) DPP4F2ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040186261-A1 Rheological adjuncts, method for production and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-09-23 US disclosed