SCHEMBL790467

SCHEMBL790467

NC(N)C(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.58
F2 P00734 1/20 0.58
HTR2A P28223 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TACR1 P25103 2/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6745618 0.81 DPP4 (0.58) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL27989314 0.81 DPP4 (0.58) DPP4F2HTR2ATAAR1ADRA2A
Hydrochloric Acid SCHEMBL1434607 0.80 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL448348 0.79 DPP4 (0.53) DPP4F2HTR2ATAAR1LMNA
Hydrochloric Acid SCHEMBL28019527 0.79 DPP4 (0.55) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1168297 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1143444 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1143202 0.79 DPP4 (0.72) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL1168170 0.77 ADRA2A (0.58) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL4451068 0.77 DPP4 (0.52) DPP4F2ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105505136-B A kind of standby UV coating of polyurethane based on cyclic carbonate ester synthesis 滁州金桥德克新材料有限公司 2018-04-17 CN claimed
EP-2616169-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS Natrix Separations Inc. (CA) 2013-07-24 EP claimed
WO-2012037101-A2 CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS NATRIX SEPARATIONS INC. (CA) 2012-03-22 WO claimed
US-20250340568-A1 SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION VERTEX PHARMA (US) 2025-11-06 US disclosed
US-20250320226-A1 METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL VERTEX PHARMA (US) 2025-10-16 US disclosed
CN-115819794-B Modified epoxy resin, preparation method thereof and UV epoxy resin pouring sealant 长春永固科技有限公司 2024-11-22 CN disclosed
CN-115401849-A Resin composition mixing device for preparing polishing pad and polishing pad preparation method SKC索密思株式会社 2022-11-29 CN disclosed
CN-115401603-A Polishing pad adhesive film, polishing pad laminate comprising same, and method for polishing wafer SKC索密思株式会社 2022-11-29 CN disclosed
CN-111378085-B Composition for polishing pad, polishing pad and preparation method thereof SKC索密思株式会社 2022-05-03 CN disclosed
CN-111378085-A Composition for polishing pad, polishing pad and preparation method thereof SKC株式会社 2020-07-07 CN disclosed
CN-111293327-A Flexible sealing sheet, flexible sealing member, and flexible sealing structure 律胜科技股份有限公司 2020-06-16 CN disclosed
EP-0104396-B1 PROCESS FOR PREPARATION OF DIAMINES OR MIXTURES OF DIAMINES BAYER AG (DE) 1985-11-13 EP disclosed
EP-0158952-A2 Triamines, a process for their preparation and their use as cross-linking agents or hardeners for plastic materials or precursors having epoxy- or isocyanate-groups BAYER AG (DE) 1985-10-23 EP disclosed
EP-0158953-A2 Triamines, a process for their preparation and their use as cross-linking agents or hardeners for plastic materials or precursers having epoxy or isocyanate-groups BAYER AG (DE) 1985-10-23 EP disclosed
EP-0104396-A1 Process for preparation of diamines or mixtures of diamines BAYER AG (DE) 1984-04-04 EP disclosed
EP-0104531-A1 Cycloaliphatic diisocyanates, possibly in the form of a mixture of isomers, method for their preparation and their use as starting products in the preparation of synthetic products of the polyurethane type BAYER AG (DE) 1984-04-04 EP disclosed
EP-0046917-B1 POLYISOCYANATE MIXTURES OF THE DIPHENYLMETHANE CLASS, AS WELL AS THEIR USE AS SYNTHESIS COMPONENTS IN THE MANUFACTURE OF POLYURETHANES BY THE ISOCYANATE-POLYADDITION PROCESS BAYER AG (DE) 1983-12-07 EP disclosed
EP-0024665-B1 DIISOCYANATES OR MIXTURES OF DIISOCYANATES OF THE DIPHENYL-METHANE SERIES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS A SYNTHESIS COMPONENT TO PRODUCE POLYURETHANE PLASTICS ACCORDING TO THE ISOCYANATE-POLYADDITION PROCESS BAYER AG (DE) 1982-05-05 EP disclosed
EP-0046917-A1 Polyisocyanate mixtures of the diphenylmethane class, as well as their use as synthesis components in the manufacture of polyurethanes by the isocyanate-polyaddition process BAYER AG (DE) 1982-03-10 EP disclosed
EP-0024665-A1 Diisocyanates or mixtures of diisocyanates of the diphenyl-methane series, process for their preparation and their use as a synthesis component to produce polyurethane plastics according to the isocyanate-polyaddition process BAYER AG (DE) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340568-A1 SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION CFTR, SLC26A4, PKD1 DPP4 1114/4885F2 1295/4885HTR2A 3653/4885
US-20250320226-A1 METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL CFTR, PKD1, AQP1 DPP4 1232/4885F2 382/4885HTR2A 1438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.