Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453395 | 1.00 | DPP4 (0.52) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL29001563 | 1.00 | DPP4 (0.52) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL29001566 | 0.87 | EPHX1 (0.43) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL29001569 | 0.87 | LMNA (0.49) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL29001567 | 0.87 | IDO1 (0.52) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL7047936 | 0.78 | KDM4E (0.65) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL19329295 | 0.78 | DPP4 (0.68) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL6745618 | 0.77 | DPP4 (0.58) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL13208856 | 0.77 | — | — | |
| SCHEMBL4348933 | 0.77 | LMNA (0.48) | DPP4F2LMNAADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114836486-B | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114836486-A | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2022-08-02 | — | — | CN | disclosed |
| US-20090036495-A1 | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists | PFIZER, INC. | 2009-02-05 | — | — | US | disclosed |
| US-7388023-B2 | Amino acids with affinity for the α2δ-protein | WARNER-LAMBERT COMPANY LLC (US) | 2008-06-17 | — | — | US | disclosed |
| US-20070191350-A1 | Combinations comprising alpha-2-delta ligands | PIFIZER INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070129550-A1 | AMINO ACIDS WITH AFFINITY FOR THE ALPHA-2-DELTA-PROTEIN | WANER-LAMBERT COMPANY LLC (US) | 2007-06-07 | — | — | US | disclosed |
| US-7179934-B2 | Amino acids with affinity for the α2δ-protein | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-20 | — | — | US | disclosed |
| US-20050124668-A1 | Amino acids with affinity for the alpha2delta-protein | WARNER-LAMBERT COMPANY LLC | 2005-06-09 | — | — | US | disclosed |
| US-20050101643-A1 | Amino acids with affinity for the alpha2delta-protein | WARNER-LAMBERT COMPANY LLC | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124668-A1 | Amino acids with affinity for the alpha2delta-protein | SCN2A, SCN1A, OPRD1 | DPP4 2680/4885F2 2661/4885LMNA 2822/4885 |
| US-20070129550-A1 | AMINO ACIDS WITH AFFINITY FOR THE ALPHA-2-DELTA-PROTEIN | SCN2A, OPRD1, SCN1A | DPP4 3263/4885F2 2280/4885LMNA 2247/4885 |
| US-20050101643-A1 | Amino acids with affinity for the alpha2delta-protein | SCN2A, OPRD1, SCN1A | DPP4 2672/4885F2 2246/4885LMNA 2797/4885 |
| US-20070191350-A1 | Combinations comprising alpha-2-delta ligands | OPRD1, CHRND, OPRL1 | DPP4 1262/4885F2 3015/4885LMNA 3586/4885 |
| US-20090036495-A1 | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists | PTGER4, PTGER2, OPRL1 | DPP4 583/4885F2 2002/4885LMNA 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.