Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 9/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220537 | 0.84 | HTR2A (0.51) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL6221138 | 0.84 | HTR1D (0.45) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL6746091 | 0.79 | HTR2A (0.47) | DRD2HTR2AHTR1AHTR6HTR7 | |
| SCHEMBL9382847 | 0.78 | ACHE (0.68) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL9133023 | 0.78 | DRD2 (0.59) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL9133222 | 0.78 | DRD2 (0.61) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL9134381 | 0.77 | DRD2 (0.58) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL6746214 | 0.77 | DRD2 (0.58) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL1545611 | 0.77 | ACHE (0.93) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL9131492 | 0.77 | DRD2 (0.60) | DRD2SLC6A4ACHEHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138230-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | ANDREANA TONJA LYNN (US) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138230-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | CNR1, DRD2, CNR2 | DRD2 2/4885SLC6A4 938/4885ACHE 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.