SCHEMBL178736

SCHEMBL178736

CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.57
KMT2A Q03164 2/20 0.54
MDM4 O15151 2/20 0.54
TP53 P04637 2/20 0.54
EPHX2 P34913 1/20 0.51
MDM2 Q00987 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26160451 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29446045 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29356265 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29401309 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29564442 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL119043 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29349978 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29508222 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL29446029 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL119044 1.00 CASP3 (0.57) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGXI NORMAL UNIVERSITY (CN) 2023-08-03 US claimed
EP-1212348-A2 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF Consensus Pharmaceuticals, Inc. (US) 2002-06-12 EP claimed
US-20020019061-A1 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF IWA, LLC 2002-02-14 US claimed
WO-2001016160-A2 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF CONSENSUS PHARMACEUTICALS, INC. (US) 2001-03-08 WO claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
CN-122075733-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 2026-05-26 CN disclosed
CN-122031713-A Preparation method and application of linker medicine and antibody-medicine conjugate thereof 乐普生物科技股份有限公司 2026-05-15 CN disclosed
EP-4602064-B1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2026-05-13 EP disclosed
EP-4659764-A1 LINKER DRUG, AND PREPARATION METHOD AND USE OF ANTIBODY-DRUG CONJUGATE THEREOF Lepu Biopharma Co., Ltd. (CN) 2025-12-10 EP disclosed
EP-4631955-A1 PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-15 EP disclosed
US-20250288587-A1 Methods of Treating Fibrosis ATHIRA PHARMA, INC. (US) 2025-09-18 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-6479508-B1 INHIBITOR OF RNA DEPENDENT RNA POLYMERASE ACTIVITY OF THE ENZYME NS5B ENCODED BY HEPATITIS C VIRUS FOR TREATMENT AND PREVENTION OF HEPATITIS C INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-11-12 US disclosed
US-6448281-B1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION; TREATMENT OF HEPATITIS C BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2002-09-10 US disclosed
EP-1212348-A2 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF Consensus Pharmaceuticals, Inc. (US) 2002-06-12 EP disclosed
US-20020019061-A1 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF IWA, LLC 2002-02-14 US disclosed
WO-2001016160-A2 PURIFICATION AND ANALYSIS OF CYCLIC PEPTIDE LIBRARIES, AND COMPOSITIONS THEREOF CONSENSUS PHARMACEUTICALS, INC. (US) 2001-03-08 WO disclosed
EP-0546055-B1 POLYETHYLENE GLYCOL DERIVATIVES FOR SOLID-PHASE APPLICATIONS UNIV MINNESOTA (US) 1996-07-10 EP disclosed
US-4914151-A Resin-linker combination for the solid-phase synthesis of peptides and intermediates BACHEM FEINCHEMIKALEIN A.G. (CH) 1990-04-03 US disclosed
US-4831084-A Resin-linker combination for the solid-phase synthesis of peptides and intermediates BACHEM FEINCHEMIKALIEN A.G. (CH) 1989-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF ACSL1, ACSL4, WEE1 CASP3 3706/4885KMT2A 3061/4885MDM4 3883/4885
US-20250288587-A1 Methods of Treating Fibrosis HDGF, HGF, MMP1 CASP3 675/4885KMT2A 3891/4885MDM4 4049/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CASP3 343/4885KMT2A 4608/4885MDM4 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.