Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973939 | 0.88 | L3MBTL1 (0.43) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL27416021 | 0.88 | L3MBTL1 (0.43) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL26054451 | 0.84 | L3MBTL1 (0.40) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL5904758 | 0.78 | L3MBTL1 (0.37) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL5904763 | 0.78 | L3MBTL1 (0.37) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL6050316 | 0.77 | SMN1; SMN2 (0.36) | GAAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL12466701 | 0.77 | L3MBTL1 (0.43) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL6050373 | 0.76 | L3MBTL1 (0.54) | L3MBTL1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL6750049 | 0.73 | MAPK8 (0.39) | GAAALDH1A1KDM4ENPSR1PPARG | |
| SCHEMBL12466679 | 0.73 | L3MBTL1 (0.43) | L3MBTL1GAAALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | CYP1A1, NOS3, NOS1 | L3MBTL1 1926/4885GAA 2723/4885ALDH1A1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.