Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5364983 | 0.99 | SIRT6 (0.52) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5352719 | 0.91 | MAPT (0.50) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5357616 | 0.81 | SIRT6 (0.65) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5352144 | 0.79 | SIRT6 (0.63) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5351218 | 0.78 | MAPT (0.47) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL5349721 | 0.77 | MAPT (0.46) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6748663 | 0.75 | MAPT (0.66) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5358867 | 0.75 | MAPT (0.46) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL15271381 | 0.75 | SIRT6 (0.81) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6151230 | 0.75 | SIRT6 (0.81) | SIRT6MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |