Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5405239 | 0.98 | MAPT (0.64) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL5357616 | 0.94 | SIRT6 (0.65) | MAPTLMNASIRT6ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5352144 | 0.92 | SIRT6 (0.63) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL5393424 | 0.90 | MAPT (0.54) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL5357980 | 0.83 | SIRT6 (0.52) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL378458 | 0.82 | MAPT (0.96) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL1851861 | 0.82 | MAPT (0.89) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL223626 | 0.80 | MAPT (1.00) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL7048817 | 0.80 | MAPT (0.85) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL85552 | 0.80 | MAPT (1.00) | MAPTLMNASIRT6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |