Sugi Predict

Sugi Predict / Compounds / SCHEMBL6746748

SCHEMBL6746748

SCHEMBL6746748

CCO[Si](C)(C)c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.39
▸ CYP1A1 P04798 2/20 0.39
▸ CYP1B1 Q16678 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ TSHR P16473 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ ERBB2 P04626 1/20 0.35
▸ FYN P06241 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ FGFR1 P11362 1/20 0.34
▸ FLT1 P17948 1/20 0.34
▸ FGFR3 P22607 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751452 0.87 CYP1A2 (0.35) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL6747101 0.84 CYP1A2 (0.41) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
SCHEMBL6748527 0.80 CYP1A2 (0.42) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
SCHEMBL6748687 0.79 ALDH1A1 (0.44) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
SCHEMBL6749563 0.79 CYP2A6 (0.37) CYP1A2ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL2950774 0.77 TP53 (0.32) CYP1A2CYP3A4
SCHEMBL6751479 0.76 ALDH1A1 (0.43) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
SCHEMBL6746739 0.71 CYP1A2 (0.43) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
SCHEMBL6745157 0.71 CYP1A2 (0.36) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL704583 0.71 NQO1 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 CYP1A2 2466/4885CYP1A1 2104/4885CYP1B1 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.