Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492272 | 0.80 | HSD11B1 (0.46) | ALDH1A1TDP1HSD11B1CYP1A2CYP3A4 | |
| SCHEMBL2089106 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TDP1POLBL3MBTL1TSHR | |
| SCHEMBL5268073 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TDP1POLBL3MBTL1TSHR | |
| SCHEMBL63469 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| SCHEMBL29441997 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| SCHEMBL476648 | 0.77 | MPL (0.40) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| SCHEMBL2036638 | 0.77 | HSD11B1 (0.40) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| Hydrogen Sulfide SCHEMBL28274662 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| SCHEMBL3249477 | 0.75 | IDO1 (0.48) | ALDH1A1TDP1POLBL3MBTL1IDO1 | |
| SCHEMBL11144791 | 0.75 | LTA4H (0.40) | ALDH1A1TDP1POLBL3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3934 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118206748-A | PCB electroplating additive and preparation method thereof | 广东利尔化学有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| EP-3778576-B1 | 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | HANLIM PHARMACEUTICAL CO LTD (KR) | 2024-04-17 | — | — | EP | claimed |
| US-20240094216-A1 | ODD CHAIN FATTY ACID THERAPY FOR THE TREATMENT OF MITOCHONDRIAL DISEASES | UNIVERSITY OF SOUTH CAROLINA | 2024-03-21 | — | — | US | claimed |
| CN-117486770-A | 2-cyanoacrylate compound and preparation method and application thereof | 贵州大学 | 2024-02-02 | — | — | CN | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| WO-2023247999-A1 | PEPTIDIC PAIN MODULATORS AND METHODS FOR PRODUCING AND USING THE SAME | MAINLINE BIOSCIENCES (SHANGHAI) CO., LTD. (CN) | 2023-12-28 | — | — | WO | claimed |
| CN-117185983-A | Bisoxindole compound, preparation method thereof and application thereof in preparation of antibacterial agent | 浙江工业大学 | 2023-12-08 | — | — | CN | claimed |
| CN-117024333-A | Oxime ether compound containing styryl and preparation method and application thereof | 贵州大学 | 2023-11-10 | — | — | CN | claimed |
| US-4117128-A | SULFONYL BENZOFURANS AND BENZOTHIOPHENES HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1978-09-26 | — | — | US | claimed |
| US-4115448-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | claimed |
| US-4112075-A | ANALGESIC, ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4022897-A | 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4010275-A | FURANOSIDES | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | claimed |
| US-3957845-A | TRIFLUOROMETHYL-SUBSTITUTED PHENYL ACETONITRILES | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1976-05-18 | — | — | US | claimed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | claimed |