Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745452 | 0.85 | SMN1; SMN2 (0.40) | KDM4EALDH1A1SMN1; SMN2CXCR1CXCR2 | |
| SCHEMBL6743776 | 0.77 | L3MBTL1 (0.44) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL28034661 | 0.73 | CYP1A2 (0.47) | KDM4EALDH1A1GAANPSR1CA12 | |
| SCHEMBL6746858 | 0.73 | KMT2A (0.37) | ALDH1A1SMN1; SMN2HSD17B10MAPTTSHR | |
| Hydrochloric Acid SCHEMBL23361661 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| Hydrochloric Acid SCHEMBL29852479 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL28788509 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL7441096 | 0.69 | GAA (0.54) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL5081589 | 0.69 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL16837304 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | KDM4E 1626/4885ALDH1A1 44/4885SMN1; SMN2 3026/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | KDM4E 1626/4885ALDH1A1 44/4885SMN1; SMN2 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.