Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746899 | 0.85 | KDM4E (0.48) | SMN1; SMN2CXCR1CXCR2POLBKMT2A | |
| SCHEMBL6746858 | 0.84 | KMT2A (0.37) | SMN1; SMN2LMNAKMT2AMEN1MAPT | |
| SCHEMBL16202049 | 0.71 | POLB (0.48) | SMN1; SMN2LMNACXCR1CXCR2POLB | |
| SCHEMBL19040400 | 0.67 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNACXCR1CXCR2POLB | |
| SCHEMBL22683805 | 0.67 | CXCR1 (0.44) | SMN1; SMN2LMNACXCR1CXCR2POLB | |
| SCHEMBL7583697 | 0.66 | TSHR (0.56) | SMN1; SMN2LMNACXCR1CXCR2POLB | |
| SCHEMBL6603038 | 0.65 | CYSLTR2 (0.54) | SMN1; SMN2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL7400285 | 0.65 | PTGS2 (0.45) | LMNAPOLBKMT2AMEN1CYP1A2 | |
| SCHEMBL6638177 | 0.64 | CXCR1 (0.55) | SMN1; SMN2LMNACXCR1CXCR2POLB | |
| SCHEMBL2547519 | 0.64 | LMNA (0.51) | SMN1; SMN2LMNACXCR1CXCR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | SMN1; SMN2 3026/4885LMNA 4406/4885CXCR1 2393/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | SMN1; SMN2 3026/4885LMNA 4406/4885CXCR1 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.